Interaction of tea catechins with lipid bilayers investigated by a quartz-crystal microbalance analysis.
نویسندگان
چکیده
The quartz-crystal microbalance (QCM) technique was applied to investigate the interaction of tea catechins with lipid bilayers. The association constants obtained from the frequency changes of QCM revealed that (-)epicatechin gallate and (-)epigallocatechin gallate interacted with 1,2-dimyristoyl-sn-glycero-3-phosphocholine ca. 1000 times more strongly than (-)epicatechin and (-)epigallocatechin. The results exhibited good correlation with the strength of biological activity.
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 72 5 شماره
صفحات -
تاریخ انتشار 2008